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Author

Genzoh Tanabe

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Open access Sep 2026

Exploring the Substrate Selectivity of the Condensation Domain VibH through Engineered Adenylation Domains, Non-Native Amide Synthesis, and Substrate Recognition Analysis.

A systematic functional analysis of VibH, a stand-alone C domain VibH from the vibriobactin biosynthetic pathway, reveals distance-dependent steric tolerance and mechanistic insights into C-domain specificity and establishes a framework for rational NRPS reprogramming.

F. Ishikawa, Hiroyuki Izuno, Shinya Nakamura et al. · 0 citations

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