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George B. Karkanias

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Review Open access Sep 2026

Targeting Dopamine Pathways for the Treatment of Tourette Syndrome

Tourette syndrome (TS) is a chronic neurodevelopmental disorder characterized by motor and vocal tics that can reduce quality of life. The pathophysiology of TS is not yet fully understood, but existing evidence implicates excess dopaminergic activity in the basal ganglia. Most pharmacotherapies for TS decrease dopam...

George B. Karkanias, John A. Flatt, Robert T. Korb et al. · 0 citations

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