Open access
Aug 2026
Clamp conformational flexibility and dynamics in archaeal and eukaryotic RNA polymerases revealed by cryo-EM
Cryo-electron microscopy is addressed using cryo-EM to examine archaeal RNAPs from Euryarchaeota and Crenarchaeota alongside yeast RNAP II and suggests that evolutionary tuning of clamp flexibility and dynamics contributes to distinct GTF-dependent promoter-loading mechanisms.
George Nkansah Rost Fordjour, L. Palao, Kenji Murakami et al.
· Journal of Biological Chemis... · 0 citations