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Observations support an oligogenic and modulatory model of HH, in which heterozygous variants in WDR11, AIRE, and FGFR1 may interact with clinical and developmental factors to determine disease severity and reversibility, and has important implications for prognosis, genetic counseling, and individualized therapeutic s...
Diminished ovarian reserve (DOR) and poor ovarian response (POR) remain among the most challenging conditions in assisted reproductive technology, and no optimal stimulation strategy has been established. Clomiphene citrate (CC), a selective estrogen receptor modulator that augments endogenous gonadotropin secretion an...
It is suggested that WHtR captures a distinct aspect of PCOS pathophysiology as it integrates both metabolic and androgenic interaction in PCOS and emerges as a pragmatic anthropometric marker for early metabolic risk stratification in PCOS.
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