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Author

Gerardo Amaya Villagran

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Review Open access Jul 2026

Human Physiology in Deep Space: Cardiovascular and Metabolic Adaptation to Long-Duration Spaceflight

Findings indicate that long-duration spaceflight should be understood as an integrated physiological challenge requiring longitudinal and individualized monitoring, and that future lunar, Martian, and deep-space missions will require combined cardiovascular, metabolic, musculoskeletal, and systemic countermeasures.

Jorge Angel Velasco Espinal, Alexa Fernanda Uriostegui Navarro, Anthony Jesús Pastrana Villares et al. · 0 citations
Review Open access Jul 2026

Liquid Biopsy in Precision Oncology: Expanding Clinical Applications for Molecular Characterization, Disease Monitoring, and Personalized Management of Solid Tumors

Overall, liquid biopsy represents a transformative strategy that complements conventional tissue biopsy and supports more personalized, dynamic, and evidence-based management of solid tumors.

Ricardo Fernando Rincón Veloz, Ana Milena Murgas Acevedo, Gerardo Amaya Villagran et al. · 0 citations
Review Open access Jul 2026

Immunosenescence in Autoimmune Rheumatic Diseases: Mechanisms, Clinical Consequences, Biomarkers, and Emerging Therapeutic Strategies

Overall, immune senescence should be recognized as a fundamental component of autoimmune rheumatic diseases, providing important opportunities for improving diagnosis, risk stratification, therapeutic decision-making, and long-term clinical outcomes in aging populations.

Benitez Barrios Sosimo Isaac, Gerardo Amaya Villagran, Nemesis Alhelí Pineda Alfaro et al. · 0 citations
Review Open access Jul 2026

Contemporary Orthogeriatric Care for Fragility Fractures: Advancing Functional Recovery and Multidisciplinary Management in Older Adults

Modern orthogeriatric care, based on multidisciplinary collaboration, timely surgical management, individualized rehabilitation, nutritional optimization, osteoporosis treatment, and secondary fracture prevention, consistently improves mobility, functional independence, postoperative outcomes, and long-term quality of...

Nilmar Del Valle Toro Arvelaiz, Diana Beatríz Alvarado Ochoa, Fabián Patricio Miranda Yáñez et al. · 0 citations
Review Open access Jul 2026

CRISPR-Based Genome Editing in Contemporary Clinical Medicine: Therapeutic Translation, Global Challenges and the Future of Precision Medicine

CRISPR has progressed from an experimental genome-engineering technology to a clinically relevant therapeutic platform, although its future impact will depend on the ability to combine molecular precision and durable therapeutic benefit with rigorous safety assessment, responsible governance, and equitable access acros...

Gabriel Alejandro Ortega Moreno, Gerardo Amaya Villagran, A. González et al. · 0 citations

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