Open access
Aug 2026
Multicellular human cardiac organoids with real-time calcium imaging enable functional modeling of heart failure and myocardial infarction.
This platform recapitulates key features of overnutrition, heart failure, and myocardial infarction, including altered contractility, calcium dynamics, and biomarker expression and provides a physiologically relevant platform for studying cardiac disease mechanisms, drug responses, and cardiotoxicity.
Vishnu Goutham Kota, S. Ganesan, Y. Ho et al.
· Acta Biochimica et Biophysic... · 0 citations