Author

Gian Marco Elisi

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Open access Sep 2026

Redox Control of S-sulfocysteine Formation in Adenosine Phosphosulfate Reductase

Sulfur assimilation fuels bacterial growth by supplying the reduced sulfur required for the biosynthesis of sulfur-containing biomolecules. Adenosine 5′-phosphosulfate reductase (APSR) catalyzes the first reductive step of this pathway, converting adenosine 5′-phosphosulfate (APS) to adenosine monophosphate. This react...

Matilda Ymeraj, Carlos A. Ramos-Guzmán, Marko Hanževački et al. · bioRxiv · 0 citations

Open access Aug 2026

Second Generation of 2,2'-Di(indol-3-yl)ethanamines as Antileishmanial Agents: Phenotypic Hit Identification and Pharmacophore Studies.

The urgent need for new antileishmanial drugs persists due to resistance and toxicity associated with current treatments. Although bisindoles represent a promising chemotype, our first-generation 2,2'-di(indol-3-yl)ethanamines, inspired by a natural marine alkaloid, displayed significant cytotoxicity despite potent act...

Gian Marco Elisi, Antonio Gkoutzamanis, S. Maestrini et al. · ACS Infectious Diseases · 0 citations