Author

Gihan F. Asaad

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Sep 2026

A Repurposed Olmesartan-Loaded Hyaluronic Acid-Functionalized Lecithin-Chitosan Nanoparticle Hydrogel for Enhanced Topical Delivery in Diabetic Wound Healing.

A novel topical nanocarrier-based hydrogel system incorporating olmesartan medoxomil (OLM) was designed to enhance diabetic wound healing through targeted skin delivery. OLM was efficiently encapsulated within lecithin-chitosan hybrid nanoparticles (LCNPs), which were subsequently functionalized with hyaluronic acid (H...

Walaa A. El-Dakroury, Gihan F. Asaad, Al-Aliaa M. Sallam et al. · Journal of drug targeting (P... · 0 citations

Open access Oct 2026

Nebivolol ameliorates CFA-induced adjuvant arthritis and is associated with reduced WNT5A and active β-catenin protein levels

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterized by synovial inflammation, cartilage destruction, bone erosion, and progressive functional impairment. Despite therapy, treatment failure and adverse effects remain major challenges. This study investigated the repurposing of nebivolol...

R. Mostafa, M. E. Shabana, Gihan F. Asaad · Scientific Reports · 0 citations

Aug 2026

Linagliptin attenuates cisplatin-induced cardiotoxicity in rats via modulation of the SIRT1/AMPK/Nrf2 signaling pathway

Linagliptin demonstrates potent cardioprotective effects against cisplatin-induced toxicity, primarily through modulation of the SIRT1/AMPK/Nrf2 signaling pathway, thereby resulting in reduced oxidative stress and inflammation.

M. Alsugoor, N. Alsuhaymi, Bassim M. S. A. Mohamed et al. · Drug and chemical toxicology... · 0 citations