Solid-State Investigation of a Novel (1:2) Venlafaxine-Catechol Cocrystal: Structural, Thermal, Spectroscopic, and Solubility Studies
This work reports the third cocrystal of venlafaxine (VLF), expanding the limited database of multicomponent solid forms of this clinically important antidepressant. A systematic cocrystal screening is conducted using a mechanochemical method and catechol (CAT) as coformer. The structure of the novel cocrystal is suc...