This study mapped whole-brain connectivity of the locus coeruleus (LC) across aging and the Alzheimer’s disease (AD) continuum and introduced a novel imaging marker called the LC gap, which quantifies deviations in LC connectivity patterns. Among several LC gap measures, left-right asymmetry was the most informative: i...
Blanca Zufiria, D. Veréb, M. Mijalkov et al.· Emerging Topics in Artificia...· 0 citations
Cognitive performance declines with aging, yet current assessment tools such as neuropsychological testing and task-based fMRI face limitations including variability, learning effects, and limited standardization. Here, we introduce in-silico cognition, a reservoir computing framework that models cognitive task perform...
M. Mijalkov, Jia-Wei Sun, Yu-Wei Chang et al.· Emerging Topics in Artificia...· 0 citations
Parkinson’s disease (PD) is a heterogeneous disorder with distinct phenotypes that may emerge years before motor diagnosis. We investigated the proposed “body-first” and “brain-first” PD phenotypes across prodromal and clinical stages using longitudinal clinical, imaging, and genetic data from 2,030 participants in the...
M. Passaretti, D. Veréb, M. Mijalkov et al.· Emerging Topics in Artificia...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
