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Giulia Colombo

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Open access Sep 2026

HLA-DQ Allele Combinations and Antibody Profiles in Children With Type 1 Diabetes: A Retrospective Study

Introduction: Type 1 diabetes (T1D) is an autoimmune disease where T cells gradually destroy pancreatic beta cells. The strongest genetic factors influencing T1D susceptibility are HLA-DQ haplotypes, which affect the variety of autoantigens presented to T cells. Islet autoantibodies, such as insulin (IAA), glutamic aci...

Donato Martella, Giulia Colombo, S. Ferraro et al. · 0 citations

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