Author

G. Ceolotto

2 papers indexed here

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Open access Oct 2026

Transcriptomic and epigenomic profiles analysis during human acclimatization to simulated high-altitude hypoxia

These findings identify distinct but overlapping phases of early HH acclimatization, progressing from stress and innate immune activation to lymphocyte-specific and redox remodeling and indicating that molecular adaptation extends beyond detectable systemic inflammatory activation.

A. Giannella, S. Mrakic-Sposta, A. Vezzoli et al. · Scientific Reports · 0 citations

Open access Aug 2026

Macrolide-Induced Aldosterone Suppression as a Functional Marker of KCNJ5-Mutated Aldosterone-Producing Adenoma: A Proof-of-Concept Clinical and Experimental Study (MAPA Study).

OBJECTIVE Primary aldosteronism (PA), the most common curable form of hypertension, is frequently caused by aldosterone-producing adenomas (APAs) harboring KCNJ5 mutations that render aldosterone synthesis sensitive to macrolides in vitro. This study aimed to evaluate whether a single dose of roxithromycin reduces plas...

G. Rossi, B. Caroccia, A. Bressan et al. · European Journal of Endocrin... · 0 citations