Hansen-guided green recovery of non-extractable hesperidin from lemon by-products with antioxidant and cholinesterase inhibitory potential.
Non-extractable phenolics (NEPs), including high-value flavonoids such as hesperidin, remain trapped in residues after conventional and advanced extraction processes, despite their recognized antioxidant and neuroprotective potential. Their sustainable recovery is key to fully valorizing citrus by-products. For the fir...