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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Graeme A. King

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Open access Sep 2026

Negative supercoiling facilitates human TOP3α-mediated decatenation of DNA braids via catenation junction melting

DNA catenation between sister chromatids arises during replication and must be efficiently resolved to ensure faithful chromosome segregation. The removal of DNA catenation is generally attributed to the type II topoisomerase TOP2α, which catalyses double-stranded DNA passage reactions and can therefore directly remove...

Sanjana Saravanan, Anno I. Koetje, Graeme A. King et al. · 0 citations

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