Open access
Sep 2026
Autopsy findings in Alzheimer's disease clinical trial participants demonstrate a high frequency of off-target coexisting pathologic features
Background Having multiple comorbid neuropathologic features may confound the results of interventional trials that were designed to target a specific pathophysiologic mechanism in Alzheimer’s disease (AD) and or related dementias (ADRD). However, it is unknown what percentage of individuals undergoing AD/ADRD interven...
E. P. Coskun, Justin M. Barber, Lauren Bojarski et al.
· The journal of prevention of... · 0 citations