Griffin P. Carter

Regulation and Characterization of the Cex system of enteric pathogens: a pathway for the lipidation and secretion of noncanoncial bacterial lipoproteins

It is shown that CexD is required for CexE’s localization to the outer leaflet of the outer membrane and that a cexD mutant of C. rodentium is attenuated in a murine model, which further define the Rns virulence regulon, the enzymology of a noncanonical acyltranferase and its contributions to pathogenicity.