Open access
Sep 2026
KARAP Deficiency Alleviates Intestinal Mucosal Barrier Dysfunction by Regulating Mitochondrial Homeostasis in Macrophages
Killer cell activating receptor-associated protein (KARAP) has been implicated in the progression of various inflammatory and immune-mediated diseases, including ulcerative colitis (UC). Although macrophages play a pivotal role in UC pathogenesis, how KARAP regulates macrophage immune responses remains poorly und...
Gui-Yuan Jin, Yong-Hong Yang, Feng-Qin Zhu et al.
· Precision Clinical Medicine · 0 citations