Feb 2026
Val325Met Mutation Affects N-glycosylation and Impairs the Function of Protein C
Background Protein C (PC) is a key anticoagulant protein that regulates hemostatic balance. Hereditary PC deficiency increases the risk of thrombosis. We identified the same mutation, c.1099G > A:p.V325 M (V325 M), in the PROC gene in four unrelated patients with thrombotic events and one patient with recurrent pregnan...
Shi-Jie Zhou, Jun-Wei Yuan, Xi Wu et al.
· Thrombosis and Haemostasis · 0 citations