Author

Guancen Lin

2 papers indexed here

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Open access Jul 2026

Multiscale higher-order molecular simplicial complex embedding for drug response prediction

Abstract Motivation Accurately predicting anticancer drug response is a central challenge in precision oncology. Existing computational methods, although valuable, often depend on pairwise molecular descriptors or limited graph-based encodings that cannot fully capture the complexity of molecular structures or their in...

Cong Shen, Guan-Cen Lin, Chuan-Shen Hu et al. · Bioinform. · 0 citations

Preprint Aug 2026

SheafIQ: Sheaf-Theoretic Information Quantification of Vector Fields on Geometric Graphs

Vector fields on graph structures naturally arise in diverse biological and engineered systems, where vector-valued states are defined on the nodes and evolve through the network interactions. Existing methods primarily characterize either the graph topology or individual signals, but generally do not quantify how loca...

Cong Shen, Guan-Cen Lin, Chuan-Shen Hu · 0 citations