Author

Guang-Dong Zhou

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Open access Oct 2026

A dual-bioeffect nanoengineered piezoelectric-photothermal hydrogel induces endochondral ossification and promotes critical-sized bone regeneration.

INTRODUCTION Critical-sized bone defects remain a major clinical challenge in orthopedics. Current strategies including inert implants and autologous bone grafts suffer from complications like loosening, infection, and donor site morbidity. Piezoelectric and photothermal stimuli synergistically regulate bone regenerati...

Chang Xu, Bao-Xing Tian, Jie Luo et al. · Journal of Advanced Research · 0 citations

Open access Sep 2026

BMSC-Based Cartilage Regeneration Units Enable Efficient Mandibular Defect Repair via Endochondral Ossification

The repair of mandibular bone defects remains a significant clinical hurdle, and tissue engineering offers an alternative strategy for reconstructive therapy. Nevertheless, conventional direct ossification is heavily dependent on a permissive microenvironment, which severely limits the regenerative outcome in large-s...

Yan-Hua Tang, Can Qiu, Yun-Zhe Zhang et al. · Regenerative Biomaterials · 0 citations

Open access Aug 2026

Phototriggered adhesive hydrogels integrating Mg/Quercetin MOFs for synchronous regulation of inflammation and angiogenesis in diabetic wounds

This in situ formed multifunctional hydrogel dressing effectively reduces excessive inflammation, enhances neovascularization, accelerates collagen tissue regeneration, and advances wound healing by improving the pathological microenvironment of diabetes.

Yunshu Yang, Bin Tang, Meng Zhou et al. · Materials Today Bio · 0 citations