Purpose: To develop a Magnetic resonance imaging (MRI) -based radiomics-clinical model for noninvasive prediction of fibroblast activation protein (FAP) expression in hepatocellular carcinoma (HCC), and to explore its association with tumor microenvironment (TME) characteristics and potential immunotherapy response. Pa...
Ruo-Lian Gao, Guang-Jie Han, Qi Wang et al.· Journal of Hepatocellular Ca...· 0 citations
Introduction Despite improved outcomes with combined hepatic arterial infusion chemotherapy (HAIC) and systemic therapy in hepatocellular carcinoma (HCC), therapeutic resistance is frequently driven by the tumor microenvironment. We aimed to explore biological features associated with therapeutic resistance in HCC. Met...
Guang-Jie Han, Li-Li Mi, Jian-Fei Shi et al.· Frontiers in Cell and Develo...· 0 citations
Background Microvascular invasion (MVI) is a remarkable factor used to predict postoperative recurrence and decide the management plan in patients with hepatocellular carcinoma (HCC). In this study, using a multiscale approach (5-, 10-, 15-mm), we investigated the biological optimal scale of radiomics features for gado...
Yan-Li Zheng, Li-Li Mi, Guang-Jie Han et al.· Frontiers in Oncology· 1 citation
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