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Author

Guang-Neng Liao

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Oct 2026

Food-Derived Extracellular Vesicles Enable Oral Liver-Targeted Delivery of Curcumin for Acute Liver Failure.

Oral delivery of water-repelling drugs for acute liver failure (ALF) often runs into problems like poor solubility, instability, and low absorption. In this work, we found that extracellular vesicles derived from honey (HEVs) can serve as a natural nanocarrier that works orally and targets the liver on its own. After i...

Xin Zeng, Wei Jiang, Lan Li et al. · 0 citations
Aug 2026

An epigenetic switch in β-cells links mitochondrial stress to inflammatory fate via HMGB1 acetylation.

A stress-responsive signalling network in which metabolic and mechanical cues are integrated at the epigenetic level to control the inflammatory fate of β-cells is unveiled, providing a new mechanistic framework for diabetic pathogenesis and a rationale for combinatorial therapeutic intervention.

Yao Cheng, Lu-Yao Wang, Xue Bai et al. · 0 citations

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