Open access
Sep 2026
Isoliensinine Suppresses Colorectal Tumorigenesis by Targeting PPP2R1A to Activate AMPK Signaling Pathway
Colorectal cancer, characterized by its invasive behavior, frequent recurrence, and limited responsiveness to standard treatment, necessitate the advancement of innovative therapeutic approaches. Isoliensinine (ISO), a natural bisbenzylisoquinoline alkaloid, has demonstrated broad antitumor activity. However, its e...
Hui Yan, Yi Huang, Xin-Ye Zheng et al.
· Food Science and Human Welln... · 0 citations