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Guang Yang

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Open access Jul 2026

The role of PlsC in Brucella melitensis virulence: impacts on membrane homeostasis, stress tolerance, and pathogenesis

Results demonstrate that PlsC is essential for maintaining membrane homeostasis and stress resistance in Brucella, which in turn supports its survival within professional phagocytes and full virulence in vivo and suggests a critical link between phospholipid metabolism and Brucella pathogenicity.

Fazhi Xu, Yao Feng, Mengsi Li et al. · 0 citations