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Guang-Ye Han

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Open access Sep 2026

The AURKA-PTTG1 signaling axis induces enzalutamide resistance in prostate cancer.

BACKGROUND Prostate cancer (PCa), a common male malignant tumor, often develops resistance to the androgen receptor inhibitor enzalutamide (ENZ). Despite its established oncogenic role, pituitary tumor-transforming gene 1 (PTTG1)'s specific function and regulatory mechanism in ENZ-resistant PCa require investigation....

Guang-Ye Han, Zhen-Hui Li, Wei-Hang Song et al. · 0 citations

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