Author

Guang-Yu Jiang

2 papers indexed here

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Open access Sep 2026

Gut microbiota dysbiosis is associated with the synaptic deficits and cognitive impairment induced by LCM mixtures within a proposed mechanistic framework consistent with the AOP concept.

It is found that long-term exposure to LCM mixtures at environmental levels more strongly inhibited viability in hippocampal HT22 cells and microglial BV2 cells than individual compounds, and was associated with memory deficits in mice accompanied by neuroinflammation and reduced hippocampal synaptic plasticity.

Lian-Rui Duan, Jia-Yi Liang, Wei Zhang et al. · Environment International · 0 citations

Aug 2026

YTHDF3-Dependent m6A Modification of cGAS Drives Nanoparticle-Induced Senescence in Spermatocytes.

BACKGROUND Nanoplastics (NPs), owing to their small size and ability to cross the blood-testis barrier, pose a potential risk to the male reproductive system. However, the molecular mechanisms underlying NP-induced reproductive toxicity, particularly cell senescence, remain poorly understood. OBJECTIVES This study ai...

Jia-Yi Liang, Wei Zhang, Hui Kang et al. · Andrology · 0 citations