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Author

Guangze Pan

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Open access Oct 2026

PSHIC reveals allele-specific chromatin organization by phasing-free structural modeling

Resolving the distinct 3D chromatin architectures of parental chromosomes is critical for understanding diploid genome function, but many haplotype-resolved Hi-C contact-map methods remain constrained by their reliance on phased single-nucleotide polymorphisms (SNPs). This dependency treats reconstruction as a simple t...

Wei Liu, Xue-Ying Wang, Yu-Wei Zhang et al. · 0 citations
Jul 2026

High-quality phage assembly from metagenomes with PALACE.

PALACE, a conjugate-graph-based framework for assembling high-quality phage genomes from metagenomes, incorporates homology-based and deep-learning-based methods to detect phage signals and constructs a conjugate graph from the metagenomic sample.

Ruohan Wang, Guangze Pan, Shuai Wang et al. · 0 citations

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