Author

Guangchao Zhao

3 papers indexed here

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Open access Sep 2026

An mPFC-DMV cortical-autonomic-immune axis governs stress-induced immune dysregulation in sepsis.

Chronic psychological stress is a major predisposing factor that worsens sepsis outcomes, yet the neural mechanisms linking stress exposure to immune dysregulation remain poorly understood. Here, using a mouse model of chronic restraint stress (CRS) followed by endotoxemia, we show that prior stress markedly aggravates...

Lu Yin, Fu-Hong Liu, Meng-Yun Li et al. · Molecular Psychiatry · 0 citations

Open access Sep 2026

Local and interregional thalamocortical dynamics show temporally dissociable changes during propofol induced loss of consciousness.

Whether propofol-induced loss of consciousness (LOC) reflects a single thalamocortical transition or involves temporally dissociable local and interregional dynamics remains unclear. Using stereo-electroencephalography recordings from the anterior nucleus of the thalamus, prefrontal cortex, and temporal cortex during a...

Lu-Xin Fan, Xin Wen, Fa Lu et al. · NeuroImage · 0 citations

Jul 2026

CB1R-dependent mitochondrial biogenesis may contribute to the antidepressant effects of esketamine in a chronic variable stress male mouse model.

Findings indicate that the antidepressant-like effects of esketamine observed 24 h after administration are associated with CB1R-dependent changes in hippocampal mitochondrial biogenesis-related protein expression, and further studies are needed to establish causality.

Wei Zhao, Xin-Xin Zhao, Yunyun Zhang et al. · Neuroscience · 0 citations