Multi-omics identifies microbial and miRNA biomarkers from rumen fluid for susceptibility of subacute ruminal acidosis in dairy goats.
A combined "microbe-miRNA" signature comprising the low-abundance genus Ruminobacter, the miRNA 7_14677, and chi-miR-361-5p was identified and exhibited high diagnostic accuracy not only between CON and SARA but also between SARA and SARA-T, as well as between pooled healthy (CON+SARA-T) and SARA animals.