Author

Guang-Ji Zhang

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Review Open access Sep 2026

Candidate Spatial Niches Associated with Gastric Cancer Metastasis and Treatment Resistance: Functional Classification, Evidence Boundaries, and a Translational Framework

A four-stage evidence framework and a minimum criteria chain are proposed to distinguish descriptive spatial patterns from candidate functional spatial niches in gastric cancer and guide future quantification, validation, and potential clinical translation in gastric cancer.

Yi Huang, Jing-Cheng Zhang, Jiaheng Lou et al. · Cells · 0 citations

Open access Jul 2026

Huangjin Shuangshen decoction alleviates chronic atrophic gastritis by suppressing TNF/NF-κB signaling and promoting CFTR-associated gastric mucosal barrier repair

HJSS alleviates MNNG-induced CAG by attenuating inflammatory injury and promoting the recovery of gastric mucosal barrier-associated molecular features, supporting an inflammation–barrier mechanism underlying the action of HJSS in CAG.

Shuo Zhang, Shuya Zhang, Mengyi Wang et al. · Frontiers in Immunology · 0 citations

Open access Jul 2026

MCT4 drives HCC progression by activating MMPs and polarizing M2 macrophages

It is demonstrated that MCT4 drives HCC progression through two complementary mechanisms: enhancing MMP-mediated invasion and metastasis, and promoting immunosuppressive M2 macrophage polarization.

Kaiyuan Zhang, Xiaochen Ni, Chuhang Wang et al. · Frontiers in Immunology · 0 citations