Review
Aug 2026
Current landscape and future perspectives of small-molecule therapeutics for Huntington's disease: From rational design to clinical translation.
This review critically summarizes the design, synthesis, and structural motifs of small-molecule candidates, clinically used agents, and antioxidant natural products, providing a structural framework to guide the rational design and development of next-generation anti-HD compounds.
Yi-Tian Jiang, Xin-Yi Chen, Zhao-Xin Xu et al.
· European journal of medicina... · 0 citations