Aug 2026
1,4,5,6-Tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidine derivatives as anti-neuroinflammatory agents: Design, synthesis, and preliminary biological evaluation.
Neuroinflammation has been identified as a causative factor of multiple neurological diseases. Microglia cells are the primary immune cells that regulate the neuroinflammation response. Hence, twenty-six 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidine derivatives (BPMs) as anti-inflammatory molecules were designed...
De-Li Xia, Yu Chen, Guang-Sen Xu et al.
· Bioorganic chemistry (Print) · 0 citations