Background Ulcerative colitis (UC) is a chronic, immune-mediated inflammatory bowel disorder, and macrophages are essential for maintaining intestinal mucosal balance during UC. Long intergenic non-coding RNA–erythroid prosurvival (lincRNA-EPS) is a novel lincRNA identified as a key inflammatory regulator. Nonetheless,...
Feng-Qin Zhu, Gui-Yuan Jin, Li-Hao Shi et al.· Frontiers in Immunology· 0 citations
Killer cell activating receptor-associated protein (KARAP) has been implicated in the progression of various inflammatory and immune-mediated diseases, including ulcerative colitis (UC). Although macrophages play a pivotal role in UC pathogenesis, how KARAP regulates macrophage immune responses remains poorly und...
This review systematically expounds on a variety of promising targeted therapeutic strategies against ETBF, clarifies their potential clinical application value and latest research progress, and provides a comprehensive theoretical framework for the clinical diagnosis, treatment and prognostic management of ETBF-associ...
Chun-Yu Wang, Li-Hao Shi, Gui-Yuan Jin et al.· Critical reviews in oncology...· 0 citations
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