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Gulsen Yilmaz

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Review Sep 2026

An Evidence-Based Biomarker Framework for n-Hexane-Induced Neuropathy: Urinary 2,5-Hexanedione, Pyrrole Adducts, and Neurofilament Light Chain.

Neuropathy induced by n-hexane is a classical toxic axonopathy caused primarily by metabolic activation of n-hexane to 2,5-hexanedione (2,5-HD). Although urinary 2,5-HD is widely used for biological monitoring, its interpretation remains complicated by analytical heterogeneity, particularly the distinction between free...

Bahadır Alikoç, Gulsen Yilmaz · 0 citations

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