Guo-Dong Feng

Escin attenuates osteoarthritis via suppressing fibroblast-like synoviocytes Jun-promoted synovial inflammation and osteoclast differentiation.

BACKGROUND Osteoarthritis (OA) is a chronic, age-related disease that severely impairs the quality of life. The pathogenesis of OA remains unknown, and current pharmacological treatments are still limited. Thus, it is urgent to identify disease targets and develop more effective therapeutic agents for OA. METHODS miR...