Open access
Aug 2026
Biohybrid Salmonella typhimurium for synergistic chemoimmunotherapy via localized chemotherapy and in situ PD-L1 blockade
A tumor-targeting Salmonella typhimurium–based platform that simultaneously enables localized chemotherapy and in situ PD-L1 blockade and underscores the promise of engineered bacterial vectors as a versatile integrated platform for targeted chemoimmunotherapy in advanced solid tumors.
Longxue Guan, Qinxiao Sun, Hancheng Jiang et al.
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