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Guo-Jun Li

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Open access Sep 2026

DiffGSP: reversing mRNA diffusion to unlock high-fidelity spatial transcriptomics

Spatial transcriptomics enables gene expression profiling within intact tissues while preserving spatial context, providing unprecedented insights into cellular organization and function. However, mRNA diffusion during tissue processing can cause transcripts originating from adjacent cells to be captured at a given spo...

Ji-Xin Liu, Shu-Li Sun, Yang Xu et al. · 0 citations

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