Diagnosis and Treatment of Patent Foramen Ovale-associated Cryptogenic Stroke.
Patent foramen ovale (PFO) is an important cause of cryptogenic stroke (CS), and its pathogenic mechanisms involve paradoxical embolism, in situ thrombus, hemodynamic changes caused by atrial remodeling, and high-risk anatomical features such as atrial septal aneurysm. Clinical assessment requires multidisciplinary eva...