Immune composition and adenosine-associated transcription in non-small-cell lung cancer after neoadjuvant PD-1 blockade.
BACKGROUND In non-small-cell lung cancer (NSCLC), high metabolic gene expression during immunotherapy can reflect either more infiltrating cells or altered cellular activity. We tested whether separating cell abundance from cell-intrinsic transcription clarifies incomplete tumour clearance after neoadjuvant programmed...