Open access
Aug 2026
METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer
The natural flavonoid luteolin is identified as an agent that upregulates METTL7A expression, which subsequently downregulates SLC1A5 expression and inhibits GC progression, and significantly enhances the efficacy of anti‐PD‐1 therapy in GC.
Mingjun Sun, Shuwei Dang, Dazhi Zhou et al.
· Advancement of science · 0 citations