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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Guoyan Liang

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Open access Aug 2026

Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD

This study identifies an RSPO2-associated NP state and a candidate WNT/FN1–CD44 programme linked to IVDD, and provides a testable basis for future WNT-directed intervention studies while recognising the limits of acute rat models and cross-species data.

Qiu-Wei Li, Guoyan Liang, Kai-Da Bo et al. · 1 citation

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