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Gurjant Singh

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Review Sep 2026

Nanotheranostics in orthopedic diseases: a critical review of molecular diagnostic-driven targeted therapeutics for personalized patient care.

INTRODUCTION Orthopedics could greatly benefit from nanotechnology, especially in drug delivery, bone tissue engineering, and implant design. Nanotheranostics represents a major step toward individualized treatment by combining diagnosis and treatment into a single nanoplatform. For orthopedic applications, nanocarrier...

Qamar Abuhassan, Husni Farah, M. Rekha et al. · 0 citations
Review Open access Aug 2026

Extracellular Vesicle-Based Approaches in Acute Myeloid Leukemia: Therapeutic Potential and Translational Challenges.

The biological roles, biomarker potential, therapeutic applications, and methodological challenges of EVs in AML are summarized and the priorities required for their future clinical development are highlighted.

G. Oriquat, Shaker Al-Hasnaawei, Hayjaa Mohaisen Mousa et al. · 0 citations
Aug 2026

Nanomedicine for biofilm associated infections: opportunities, challenges, and clinical translation

Comparative studies suggest that combination approaches, including enzyme functionalized or stimuli responsive nanoparticles paired with antibiotics, may outperform single modality treatments by simultaneously disrupting the biofilm matrix and delivering active agents.

Husni Farah, Munthar Kadhim-Abosaoda, Hayjaa Mohaisen-Mousa et al. · 0 citations
Review Sep 2026

Clinical translation of mRNA-based cancer vaccines for solid tumors.

Evidence from published clinical studies and 65 registered clinical trials on mRNA-based cancer vaccines are synthesized, summarizing key molecular principles, delivery strategies, clinical translation in solid tumors, and ongoing opportunities for future therapeutic development are summarized.

Zahraa A. Alkhafaje, M. H., Aniruddh Dash et al. · 0 citations
Review Open access Aug 2026

Tumor‐Associated Macrophages in the Chemoresistant Microenvironment of Gastric Cancer: Key Mechanisms and Intercellular Crosstalk

Current evidence on TAM‐driven chemoresistance in GC is synthesized, highlighting the molecular interplay between TAMs, tumor cells, and stromal components and underscores the potential of TAM‐centric therapies to overcome resistance and improve clinical outcomes.

S. Abdul-Rahman, Abdulkareem Shareef, S. Jyothi et al. · 0 citations

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