Dengue virus (DENV) continues to expand globally, with increasing incidence in both endemic and non-endemic countries. Leveraging a large global dataset of DENV genomes starting from the 1940s, we reconstructed global and regional patterns of DENV spread using phylogeographic and phylodynamic methods. Our analyses reve...
Verity Hill, G. Dudas, Xiang Ji et al.· bioRxiv· 1 citation
Bayesian phylogenetic and phylodynamic analyses can be very time-consuming, owing to the combination of complex models that are used to estimate key parameters from increasingly large genomic data sets and their associated metadata. The use of high-performance computer hardware can -- to a certain extent -- alleviate t...
M. Brusselmans, Guy Baele, S. Hong et al.· 0 citations
These detections revealed a Southern Ocean pathway of recurrent H5N1 incursions into Australia, highlighting the risk of potential establishment on the mainland and the need for heightened surveillance and rapid, nationally-coordinated, virus genomic characterisation.
Matthew J. Neave, S. Hair, Patrick Mileto et al.· bioRxiv· 1 citation
BACKGROUND
Rodent-borne pathogens pose important global health risks, yet national-scale assessments linking host-pathogen ecology with disease dynamics remain limited, particularly in China.
METHODS
We compiled global (>29,000 records) and China-specific (2,235 records; 1950-2023) rodent-pathogen datasets to charact...
Hong-Yan Wu, Kang Yu, Yu-Run Xue et al.· Journal of Infection· 0 citations
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