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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Gyu Na Kim

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Sep 2026

Physicochemical and biological evaluation of a GMP‑grade ionizable lipid for robust and scalable manufacturing of siRNA- and mRNA-loaded lipid nanoparticles.

The clinical translation of RNA-loaded lipid nanoparticles (LNPs) requires GMP-grade excipients supported by a rigorous analytical control strategy. This study aimed to evaluate the GMP-grade ionizable lipid (YCE-C10) as a manufacturing-ready component for siRNA- and mRNA-loaded LNPs produced by scalable microfluidic m...

R. Maharjan, Gyu Na Kim, Hun Soon Jung et al. · 0 citations

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