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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

H. A. Natarajan

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Review Sep 2026

Efficacy and cardiovascular safety of lasmiditan in patients with cardiovascular risk factors: A systematic review and meta-analysis with updated synthesis of triptan safety data.

OBJECTIVE This study was conducted to evaluate lasmiditan efficacy and cardiovascular (CV) safety in patients with CV risk factors, and provide an updated synthesis of observational evidence on long-term triptan-related CV outcomes. BACKGROUND Approximately 20% of patients with migraine have CV contraindications to t...

Shankar Biswas, S. Vasireddy, Yashasvi Srivastava et al. · 0 citations
Review Open access Sep 2026

Efficacy and Safety of Macitentan Across Pulmonary Hypertension Phenotypes: A Systematic Review and Meta-analysis

Macitentan-containing therapy was associated with favorable changes in selected hemodynamic outcomes but not with a statistically significant improvement in 6MWD or mPAP, and the safety findings were characterized by higher risks of anemia, peripheral edema, and treatment discontinuation.

S. Gurram, V. Mp, S. Avula et al. · 0 citations

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