Impact of 3D Culture Systems for Mesenchymal Stromal Cells on the Secretion of Growth Differentiation Factor 5 and the Implications for Cartilage Regeneration
The poor regenerative capacity of articular cartilage and the limited efficacy of current treatments in restoring its extracellular matrix contribute to osteoarthritis. This study investigated an emerging approach using the secretome of mesenchymal stromal cells (MSC) to stimulate chondrocyte-driven cartilage matrix sy...