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H. C. Machado

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Open access Oct 2026

Methadone versus morphine for postoperative analgesia in gynecological laparoscopy: protocol for a randomized controlled trial

Background: Methadone has unique pharmacological properties among opioids, including N-methyl-D-aspartate receptor antagonism and a long half-life, which may enhance postoperative analgesia. Evidence regarding its efficacy and safety in gynecological laparoscopic surgery remains limited. This study protocol will compar...

Idelberto Do Val Ribeiro-Junior, L. Brito, Ana Paula da Silva Rios et al. · 0 citations

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