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H. Nguyen

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Sep 2026

Multi-tiered in silico evaluation identifies Sarsasapogenin as a promising ERα-targeted phytochemical against breast cancer.

Sarsasapogenin, a spirostanol sapogenin with reported activity against ERα-positive breast cancer cells, has no defined molecular target, and its metabolic fate has not been considered in computational studies of this compound class. Network pharmacology, biotransformation profiling, and multi-level molecular modeling...

S. D. Thuong, T. Từ, N. Nguyễn et al. · 0 citations
Open access Aug 2026

Mechanistic insights into daidzin from Glycine max against breast cancer via network pharmacology and multi-level molecular modeling

An integrated in silico strategy combining network pharmacology and molecular modeling is used to prioritize daidzin targets and validate key interactions, with sirtinol as a reference compound, and prioritize a daidzin-MMP9 axis for experimental validation.

Lan Thị Vũ, L. T. Vũ, Lien Thi Kim Vu et al. · 0 citations

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