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Author

H. Erdem

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Review Open access Oct 2026

HBOCpred: An Ensemble Framework for Prioritisation of Germline Missense Variants in Hereditary Breast and Ovarian Cancer

HBOCpred was developed to support research prioritisation of unresolved germline missense variants in a defined 17-gene study panel. Four calibrated learners provide vote states (V0–V4) and a continuous modified adaptive classifier score (SMAC). The same directional descriptors apply to labelled and unresolved records:...

M. Alay, H. Erdem · 0 citations

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