In Vitro Binding to a Mitochondrial G-Quadruplex-Forming Sequence and Exploratory Acute Tolerability Assessment of a Cyclic Anthraquinone Anticancer Agent
G-quadruplexes (G4s) have attracted considerable attention as molecular targets for the development of anticancer agents with improved selectivity and safety profiles. Cyclic anthraquinone derivatives have been developed as G4-binding ligands, and our previous studies demonstrated that cAQ-mBen preferentially binds to...